Endocrine Abstracts

Objective: To investigate the association between cigarette smoking and the progression of diabetic nephropathy in type 1 diabetic patients.Research design and methods: A prospective, follow-up study over 1 year was conducted in a sequential sample of 30 smokers, 30 nonsmokers, and 30 ex-smokers with type 1 diabetes, hypertension, and diabetic nephropathy. Progression of renal disease was defined according to the stage of nephropathy as an increase in pr...

Background: Medullary thyroid carcinoma (MTC) is characterised by a high concentration of serum calcitonin. Routine measurement of serum calcitonin concentration has been advocated for detection of MTC among patients with nodular thyroid diseases. The aims of our study were to identify medullary thyroid cancer (MTC) in its earliest stages by screening patients with basal calcitonin measurements and to determine whether basal serum calcitonin measurements should be a part of ou...

Introduction: Metformin is the first line treatment of type 2 diabetes, but now has been reported to cause a decrease in level of Vitamin B12.The aim of the study is to describe the prevalence of vitamin B12 deficiency in adults with type 2 Diabetes Mellitus who were in treatment with metformin compared in those without diabetes.Material and Methods: Total number of patients were 130 between 16–84 years old. Mean age 54.2 &#1...

Introduction: Elevated blood pressure levels are more frequently observed in diabetic patients, than in the general population. Ambulatory blood pressure monitoring (ABPM) is better correlated with target organ damage from hypertension (HT) than clinic blood pressure readings. The correlation between ABPM and urinary albumin excretion rate (UAER) in diabetes mellitus (DM) has been found to be stronger than the correlation between clinic blood pressure (BP) and UAER.<p clas...

Aim: The aim of this study was to determine the relationship between subclinical hypothyroidism and prevalence of nephropathy and cardiovascular disease in type 2 diabetic patients without taking thyroid medication.Methods: Serum thyrotropin and free thyroxine concentrations were measured in 50 type 2 diabetic subjects in DC ‘Ikeda-Euromedica’ and DC ‘Med.al’ in Tirana, from September 2009 until September 2012. In a cross-sectional st...